Rumored Buzz on THCA natural effect
To circumvent the lower reactivity, MeLi was used to produce the lithio enolate intermediates that are much more reactive in direction of electrophiles. To demonstrate the principle, cyclohexenone fifty one was activated with boron trifluoride, arylated with 38, reworked in the enolate employing MeLi, and finally phosphorylated working with diethyl